Antiviral and interferon-inducing properties of interferon inducers administered with prostaglandins.
نویسنده
چکیده
Prostaglandins enhanced the interferon response and therapeutic activity of interferon inducers in Friend leukemia virus-infected mice. A similar enhancement in interfron responsiveness but not antiviral activity was observed in mice infected with rapidly acute viruses.
منابع مشابه
Antiviral and interferon-inducing properties of 1,5-diamino anthraquinones.
A series of anthraquinones with amino substituents at the 1,5 positions were found to induce interferon in mice. A prototype compound, 1,5-bis[(3-morpholinopropyl)amino]-anthraquinone (Ia), was an effective antiviral agent when administered either orally or parenterally. Peak interferon titers were found 12 to 24 h after drug treatment. The minimum oral dose of Ia required to induce serum inter...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 17 3 شماره
صفحات -
تاریخ انتشار 1980